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Identification of neutral tumor evolution across cancer types
Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic data in the light of cancer evolution remains challenging. Here we demonstrate that neutral tumor evolution results in a power-law distribution of the mutant allele frequencies reported by next-generatio...
| Главные авторы: | , , , , |
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| Формат: | Online Статья Текст |
| Язык: | English |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934603/ https://www.ncbi.nlm.nih.gov/pubmed/26780609 http://dx.doi.org/10.1038/ng.3489 |