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Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults

Offspring of older mothers are at increased risk of adverse birth outcomes, childhood cancers, type 1 diabetes, and neurodevelopmental disorders. The underlying biologic mechanisms for most of these associations remain obscure. One possibility is that maternal aging may produce lasting changes in th...

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Detalles Bibliográficos
Autores principales: Markunas, Christina A., Wilcox, Allen J., Xu, Zongli, Joubert, Bonnie R., Harlid, Sophia, Panduri, Vijayalakshmi, Håberg, Siri E., Nystad, Wenche, London, Stephanie J., Sandler, Dale P., Lie, Rolv T., Wade, Paul A., Taylor, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934688/
https://www.ncbi.nlm.nih.gov/pubmed/27383059
http://dx.doi.org/10.1371/journal.pone.0156361