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A triangular connection between Cyclin G, PP2A and Akt1 in the regulation of growth and metabolism in Drosophila

Size and weight control is a tightly regulated process, involving the highly conserved Insulin receptor/target of rapamycin (InR/TOR) signaling cascade. We recently identified Cyclin G (CycG) as an important modulator of InR/TOR signaling activity in Drosophila. cycG mutant flies are underweight and...

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Detalles Bibliográficos
Autores principales: Fischer, Patrick, Preiss, Anette, Nagel, Anja C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934794/
https://www.ncbi.nlm.nih.gov/pubmed/26980713
http://dx.doi.org/10.1080/19336934.2016.1162362