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Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model

We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting. We characterized the changes in cardiac structure and function in response to chronic isoproterenol in...

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Detalles Bibliográficos
Autores principales: Wang, Jessica Jen-Chu, Rau, Christoph, Avetisyan, Rozeta, Ren, Shuxun, Romay, Milagros C., Stolin, Gabriel, Gong, Ke Wei, Wang, Yibin, Lusis, Aldons J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934852/
https://www.ncbi.nlm.nih.gov/pubmed/27385019
http://dx.doi.org/10.1371/journal.pgen.1006038