Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner

Hepatitis C virus (HCV) induces interferon (IFN) stimulated genes in the liver despite of distinct innate immune evasion mechanisms, suggesting that beyond HCV infected cells other cell types contribute to innate immune activation. Upon coculture with HCV replicating cells, human CD141(+) myeloid de...

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Detalles Bibliográficos
Autores principales: Pfaender, Stephanie, Grabski, Elena, Detje, Claudia N., Riebesehl, Nina, Lienenklaus, Stefan, Steinmann, Eike, Kalinke, Ulrich, Pietschmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934921/
https://www.ncbi.nlm.nih.gov/pubmed/27385030
http://dx.doi.org/10.1371/journal.ppat.1005736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934921/
https://www.ncbi.nlm.nih.gov/pubmed/27385030
http://dx.doi.org/10.1371/journal.ppat.1005736

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