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Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner
Hepatitis C virus (HCV) induces interferon (IFN) stimulated genes in the liver despite of distinct innate immune evasion mechanisms, suggesting that beyond HCV infected cells other cell types contribute to innate immune activation. Upon coculture with HCV replicating cells, human CD141(+) myeloid de...
Autores principales: | Pfaender, Stephanie, Grabski, Elena, Detje, Claudia N., Riebesehl, Nina, Lienenklaus, Stefan, Steinmann, Eike, Kalinke, Ulrich, Pietschmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934921/ https://www.ncbi.nlm.nih.gov/pubmed/27385030 http://dx.doi.org/10.1371/journal.ppat.1005736 |
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