Alpha-2A Adrenoceptor Agonist Guanfacine Restores Diuretic Efficiency in Experimental Cirrhotic Ascites: Comparison with Clonidine

BACKGROUND: In human cirrhosis, adrenergic hyperfunction causes proximal tubular fluid retention and contributes to diuretic-resistant ascites, and clonidine, a sympatholytic drug, improves natriuresis in difficult-to-treat ascites. AIM: To compare clonidine (aspecific α(2)-adrenoceptor agonist) to...

Descripción completa

Detalles Bibliográficos
Autores principales: Sansoè, Giovanni, Aragno, Manuela, Mastrocola, Raffaella, Mengozzi, Giulio, Parola, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934922/
https://www.ncbi.nlm.nih.gov/pubmed/27384184
http://dx.doi.org/10.1371/journal.pone.0158486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934922/
https://www.ncbi.nlm.nih.gov/pubmed/27384184
http://dx.doi.org/10.1371/journal.pone.0158486

Ejemplares similares