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Metabolic fate of poly-(lactic-co-glycolic acid)-based curcumin nanoparticles following oral administration

PURPOSE: Curcumin (CUR), the main polyphenol in turmeric, is poorly absorbed and rapidly metabolized following oral administration, which severely curtails its bioavailability. Poly-(lactic-co-glycolic acid)-based CUR nanoparticles (CUR-NP) have recently been suggested to improve CUR bioavailability...

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Detalles Bibliográficos
Autores principales: Harigae, Takahiro, Nakagawa, Kiyotaka, Miyazawa, Taiki, Inoue, Nao, Kimura, Fumiko, Ikeda, Ikuo, Miyazawa, Teruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935090/
https://www.ncbi.nlm.nih.gov/pubmed/27418823
http://dx.doi.org/10.2147/IJN.S107442