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Metabolic fate of poly-(lactic-co-glycolic acid)-based curcumin nanoparticles following oral administration
PURPOSE: Curcumin (CUR), the main polyphenol in turmeric, is poorly absorbed and rapidly metabolized following oral administration, which severely curtails its bioavailability. Poly-(lactic-co-glycolic acid)-based CUR nanoparticles (CUR-NP) have recently been suggested to improve CUR bioavailability...
Autores principales: | Harigae, Takahiro, Nakagawa, Kiyotaka, Miyazawa, Taiki, Inoue, Nao, Kimura, Fumiko, Ikeda, Ikuo, Miyazawa, Teruo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935090/ https://www.ncbi.nlm.nih.gov/pubmed/27418823 http://dx.doi.org/10.2147/IJN.S107442 |
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