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Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression

Thyroid cancer is the most common endocrine malignancy and accounts for the majority of endocrine cancer-related deaths each year. Our group and others have previously demonstrated dysfunctional microRNA (miRNA or miR) expression in the context of thyroid cancer. The objective of the present study w...

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Detalles Bibliográficos
Autores principales: Aherne, Sinéad T., Smyth, Paul, Freeley, Michael, Smith, Leila, Spillane, Cathy, O'leary, John, Sheils, Orla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935456/
https://www.ncbi.nlm.nih.gov/pubmed/27353001
http://dx.doi.org/10.3892/ijmm.2016.2653