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CRM-1 knockdown inhibits extrahepatic cholangiocarcinoma tumor growth by blocking the nuclear export of p27(Kip1)

Cholangiocarcinoma is a deadly disease which responds poorly to surgery and conventional chemotherapy or radiotherapy. Early diagnosis is difficult due to the anatomical and biological characteristics of cholangiocarcinoma. Cyclin-dependent kinase inhibitor 1B (p27(Kip1)) is a cyclin-dependent kinas...

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Detalles Bibliográficos
Autores principales: Luo, Jian, Chen, Yongjun, Li, Qiang, Wang, Bing, Zhou, Yanqiong, Lan, Hongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935460/
https://www.ncbi.nlm.nih.gov/pubmed/27279267
http://dx.doi.org/10.3892/ijmm.2016.2628