Early postnatal GABA(A) receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1

Exploring drug targets based on disease-associated molecular mechanisms during development is crucial for the generation of novel prevention and treatment strategies for neurodevelopmental psychiatric conditions. We report that prefrontal cortex-specific postnatal knockdown of DISC1 via in utero ele...

Descripción completa

Detalles Bibliográficos
Autores principales: Saito, Atsushi, Taniguchi, Yu, Rannals, Matthew D., Merfeld, Emily B., Ballinger, Michael D., Koga, Minori, Ohtani, Yoshikazu, Gurley, David A., Sedlak, Thomas W., Cross, Alan, Moss, Stephen J., Brandon, Nicholas J., Maher, Brady J., Kamiya, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935661/
https://www.ncbi.nlm.nih.gov/pubmed/26728564
http://dx.doi.org/10.1038/mp.2015.203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935661/
https://www.ncbi.nlm.nih.gov/pubmed/26728564
http://dx.doi.org/10.1038/mp.2015.203

Ejemplares similares