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A Simplified In vitro Experimental Model Encompasses the Essential Features of Sleep

In this paper, we show that neuronal assemblies plated on Micro Electrode Arrays present synchronized, low frequency firing patterns similar to in vivo slow wave oscillations, which are a key parameter of sleep-like state. Although neuronal cultures lack the characteristic high-frequency waves of wa...

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Detalles Bibliográficos
Autores principales: Colombi, Ilaria, Tinarelli, Federico, Pasquale, Valentina, Tucci, Valter, Chiappalone, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935686/
https://www.ncbi.nlm.nih.gov/pubmed/27458335
http://dx.doi.org/10.3389/fnins.2016.00315