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A Simplified In vitro Experimental Model Encompasses the Essential Features of Sleep
In this paper, we show that neuronal assemblies plated on Micro Electrode Arrays present synchronized, low frequency firing patterns similar to in vivo slow wave oscillations, which are a key parameter of sleep-like state. Although neuronal cultures lack the characteristic high-frequency waves of wa...
Autores principales: | Colombi, Ilaria, Tinarelli, Federico, Pasquale, Valentina, Tucci, Valter, Chiappalone, Michela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935686/ https://www.ncbi.nlm.nih.gov/pubmed/27458335 http://dx.doi.org/10.3389/fnins.2016.00315 |
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