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Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites

Malaria is a worldwide disease caused by Plasmodium parasites. A sesquiterpene endoperoxide artemisinin isolated from Artemisia annua was discovered and has been accepted for its use in artemisinin-based combinatorial therapies, as the most effective current antimalarial treatment. However, the quan...

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Detalles Bibliográficos
Autores principales: Muangphrom, Paskorn, Seki, Hikaru, Fukushima, Ery Odette, Muranaka, Toshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935751/
https://www.ncbi.nlm.nih.gov/pubmed/27250562
http://dx.doi.org/10.1007/s11418-016-1008-y