Cargando…

The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex

Forkhead-box domain (Fox) containing family members are known to play a role in neocorticogenesis and have also been associated with disorders on the autism spectrum. Here we show that a single RNA-binding protein, Hu antigen R (HuR), dictates translation specificity of bound mRNAs and is sufficient...

Descripción completa

Detalles Bibliográficos
Autores principales: Popovitchenko, T., Thompson, K., Viljetic, B., Jiao, X., Kontonyiannis, D. L., Kiledjian, M., Hart, R. P., Rasin, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935837/
https://www.ncbi.nlm.nih.gov/pubmed/27383233
http://dx.doi.org/10.1038/srep28998