Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants

Pre-eclampsia is a common pregnancy disorder that is a major cause for maternal and perinatal mortality and morbidity. Variants predisposing to pre-eclampsia might be under negative evolutionary selection that is likely to keep their population frequencies low. We exome sequenced samples from a hund...

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Detalles Bibliográficos
Autores principales: Kaartokallio, Tea, Wang, Jingwen, Heinonen, Seppo, Kajantie, Eero, Kivinen, Katja, Pouta, Anneli, Gerdhem, Paul, Jiao, Hong, Kere, Juha, Laivuori, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935848/
https://www.ncbi.nlm.nih.gov/pubmed/27384325
http://dx.doi.org/10.1038/srep29085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935848/
https://www.ncbi.nlm.nih.gov/pubmed/27384325
http://dx.doi.org/10.1038/srep29085

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