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Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants
Pre-eclampsia is a common pregnancy disorder that is a major cause for maternal and perinatal mortality and morbidity. Variants predisposing to pre-eclampsia might be under negative evolutionary selection that is likely to keep their population frequencies low. We exome sequenced samples from a hund...
Autores principales: | Kaartokallio, Tea, Wang, Jingwen, Heinonen, Seppo, Kajantie, Eero, Kivinen, Katja, Pouta, Anneli, Gerdhem, Paul, Jiao, Hong, Kere, Juha, Laivuori, Hannele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935848/ https://www.ncbi.nlm.nih.gov/pubmed/27384325 http://dx.doi.org/10.1038/srep29085 |
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