Cargando…

Protease activated receptor 1 (PAR1) enhances Src-mediated tyrosine phosphorylation of NMDA receptor in intracerebral hemorrhage (ICH)

It has been demonstrated that Src could modulate NMDA receptor, and PAR1 could also affect NMDAR signaling. However, whether PAR1 could regulate NMDAR through Src under ICH has not yet been investigated. In this study, we demonstrated the role of Src-PSD95-GluN2A signaling cascades in rat ICH model...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Zhen-Zhen, Zhang, Feng, Li, Feng-Ying, Luan, Yi-Fei, Guo, Peng, Li, Yi-Hang, Liu, Yong, Qi, Su-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935874/
https://www.ncbi.nlm.nih.gov/pubmed/27385592
http://dx.doi.org/10.1038/srep29246