Stiffness of the microenvironment upregulates ERBB2 expression in 3D cultures of MCF10A within the range of mammographic density

The effects of the stiffness of the microenvironment on the molecular response of 3D colony organization, at the maximum level of mammographic density (MD), are investigated. Phenotypic profiling reveals that 3D colony formation is heterogeneous and increased stiffness of the microenvironment, withi...

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Detalles Bibliográficos
Autores principales: Cheng, Qingsu, Bilgin, Cemal Cagatay, Fonteney, Gerald, Chang, Hang, Henderson, Matthew, Han, Ju, Parvin, Bahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935956/
https://www.ncbi.nlm.nih.gov/pubmed/27383056
http://dx.doi.org/10.1038/srep28987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935956/
https://www.ncbi.nlm.nih.gov/pubmed/27383056
http://dx.doi.org/10.1038/srep28987

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