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Stiffness of the microenvironment upregulates ERBB2 expression in 3D cultures of MCF10A within the range of mammographic density
The effects of the stiffness of the microenvironment on the molecular response of 3D colony organization, at the maximum level of mammographic density (MD), are investigated. Phenotypic profiling reveals that 3D colony formation is heterogeneous and increased stiffness of the microenvironment, withi...
Autores principales: | Cheng, Qingsu, Bilgin, Cemal Cagatay, Fonteney, Gerald, Chang, Hang, Henderson, Matthew, Han, Ju, Parvin, Bahram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935956/ https://www.ncbi.nlm.nih.gov/pubmed/27383056 http://dx.doi.org/10.1038/srep28987 |
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