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Fluorescent imaging of superficial head and neck squamous cell carcinoma using a γ-glutamyltranspeptidase-activated targeting agent: a pilot study

BACKGROUND: Detecting superficial head and neck squamous cell carcinoma (HNSCC) by endoscopy is challenging because of limited morphological hallmarks, and iodine cannot be applied to head and neck lesions due to severe mucosal irritation. γ-glutamyltranspeptidase (GGT), a cell surface enzyme, is ov...

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Detalles Bibliográficos
Autores principales: Mizushima, Takeshi, Ohnishi, Shunsuke, Shimizu, Yuichi, Hatanaka, Yutaka, Hatanaka, Kanako C., Hosono, Hidetaka, Kubota, Yoshimasa, Natsuizaka, Mitsuteru, Kamiya, Mako, Ono, Shouko, Homma, Akihiro, Kato, Mototsugu, Sakamoto, Naoya, Urano, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936014/
https://www.ncbi.nlm.nih.gov/pubmed/27387955
http://dx.doi.org/10.1186/s12885-016-2421-z