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Early Loss of Telomerase Action in Yeast Creates a Dependence on the DNA Damage Response Adaptor Proteins

Telomeres cap the ends of chromosomes, protecting them from degradation and inappropriate DNA repair processes that can lead to genomic instability. A short telomere elicits increased telomerase action on itself that replenishes telomere length, thereby stabilizing the telomere. In the prolonged abs...

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Detalles Bibliográficos
Autores principales:	Jay, Kyle A., Smith, Dana L., Blackburn, Elizabeth H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936065/ https://www.ncbi.nlm.nih.gov/pubmed/27161319 http://dx.doi.org/10.1128/MCB.00943-15

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