A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2C(ATPase) Causes Conditional Defects in Encapsidation and Uncoating

The specificity of encapsidation of C-cluster enteroviruses depends on an interaction between capsid proteins and nonstructural protein 2C(ATPase). In particular, residue N(252) of poliovirus 2C(ATPase) interacts with VP3 of coxsackievirus A20, in the context of a chimeric virus. Poliovirus 2C(ATPas...

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Detalles Bibliográficos
Autores principales: Asare, Emmanuel, Mugavero, JoAnn, Jiang, Ping, Wimmer, Eckard, Paul, Aniko V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Structure and Assembly
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936127/
https://www.ncbi.nlm.nih.gov/pubmed/27076638
http://dx.doi.org/10.1128/JVI.02877-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936127/
https://www.ncbi.nlm.nih.gov/pubmed/27076638
http://dx.doi.org/10.1128/JVI.02877-15

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