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Auto-thiophosphorylation activity of Src tyrosine kinase

BACKGROUND: Intermolecular autophosphorylation at Tyr416 is a conserved mechanism of activation among the members of the Src family of nonreceptor tyrosine kinases. Like several other tyrosine kinases, Src can catalyze the thiophosphorylation of peptide and protein substrates using ATPγS as a thioph...

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Detalles Bibliográficos
Autores principales: Cabail, M. Zulema, Chen, Emily I., Koller, Antonius, Miller, W. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936181/
https://www.ncbi.nlm.nih.gov/pubmed/27387461
http://dx.doi.org/10.1186/s12858-016-0071-z