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Functional and molecular evidence for heteromeric association of P2Y(1) receptor with P2Y(2) and P2Y(4) receptors in mouse granulocytes

BACKGROUND: All hematopoietic cells express P2 receptors, however pharmacological characteristics such as expression and affinity in granulocytes are unknown. METHODS: Pharmacological characteristics of P2 receptors were evaluated by Ca(2+) measurements using Fura-2 fluorophore. P2 receptors express...

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Detalles Bibliográficos
Autores principales: Ribeiro-Filho, Antonio Carlos, Buri, Marcus Vinicius, Barros, Carlos Castilho, Dreyfuss, Juliana Luporini, Nader, Helena Bonciani, Justo, Giselle Zenker, Craveiro, Rogério Bastos, Pesquero, João Bosco, Miranda, Antonio, Ferreira, Alice Teixeira, Paredes-Gamero, Edgar Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936188/
https://www.ncbi.nlm.nih.gov/pubmed/27384918
http://dx.doi.org/10.1186/s40360-016-0072-y