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Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo

BACKGROUND: Biological applications of nanoparticles are rapidly increasing, which introduces new possibilities to improve the efficacy of radiotherapy. Here, we synthesized titanium peroxide nanoparticles (TiOxNPs) and investigated their efficacy as novel agents that can potently enhance the effect...

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Detalles Bibliográficos
Autores principales: Nakayama, Masao, Sasaki, Ryohei, Ogino, Chiaki, Tanaka, Tsutomu, Morita, Kenta, Umetsu, Mitsuo, Ohara, Satoshi, Tan, Zhenquan, Nishimura, Yuya, Akasaka, Hiroaki, Sato, Kazuyoshi, Numako, Chiya, Takami, Seiichi, Kondo, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936232/
https://www.ncbi.nlm.nih.gov/pubmed/27386977
http://dx.doi.org/10.1186/s13014-016-0666-y