EGFR gene amplification is relatively common and associates with outcome in intestinal adenocarcinoma of the stomach, gastro-oesophageal junction and distal oesophagus

BACKGROUND: Approximately 50 % of gastric adenocarcinomas belong to a molecular subgroup characterised by chromosomal instability and a strong association with the intestinal histological subtype. This subgroup typically contains alterations in the receptor tyrosine kinase–RAS pathway, for example E...

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Detalles Bibliográficos
Autores principales: Birkman, Eva-Maria, Ålgars, Annika, Lintunen, Minnamaija, Ristamäki, Raija, Sundström, Jari, Carpén, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936304/
https://www.ncbi.nlm.nih.gov/pubmed/27387915
http://dx.doi.org/10.1186/s12885-016-2456-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936304/
https://www.ncbi.nlm.nih.gov/pubmed/27387915
http://dx.doi.org/10.1186/s12885-016-2456-1

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