Somatic ERCC2 Mutations Are Associated with a Distinct Genomic Signature in Urothelial Tumors

Alterations in DNA repair pathways are common in tumors and can result in characteristic mutational signatures; however, a specific mutational signature associated with somatic alterations in the nucleotide excision repair (NER) pathway has not yet been identified. Here, we examine the mutational pr...

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Detalles Bibliográficos
Autores principales: Kim, Jaegil, Mouw, Kent W, Polak, Paz, Braunstein, Lior Z, Kamburov, Atanas, Kwiatkowski, David J, Rosenberg, Jonathan E, Van Allen, Eliezer M, D'Andrea, Alan, Getz, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936490/
https://www.ncbi.nlm.nih.gov/pubmed/27111033
http://dx.doi.org/10.1038/ng.3557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936490/
https://www.ncbi.nlm.nih.gov/pubmed/27111033
http://dx.doi.org/10.1038/ng.3557

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