Cargando…
Somatic ERCC2 Mutations Are Associated with a Distinct Genomic Signature in Urothelial Tumors
Alterations in DNA repair pathways are common in tumors and can result in characteristic mutational signatures; however, a specific mutational signature associated with somatic alterations in the nucleotide excision repair (NER) pathway has not yet been identified. Here, we examine the mutational pr...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936490/ https://www.ncbi.nlm.nih.gov/pubmed/27111033 http://dx.doi.org/10.1038/ng.3557 |