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DNA Damage Response in Hematopoietic Stem Cell Ageing

Maintenance of tissue-specific stem cells is vital for organ homeostasis and organismal longevity. Hematopoietic stem cells (HSCs) are the most primitive cell type in the hematopoietic system. They divide asymmetrically and give rise to daughter cells with HSC identity (self-renewal) and progenitor...

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Detalles Bibliográficos
Autores principales: Li, Tangliang, Zhou, Zhong-Wei, Ju, Zhenyu, Wang, Zhao-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936660/
https://www.ncbi.nlm.nih.gov/pubmed/27221660
http://dx.doi.org/10.1016/j.gpb.2016.04.002