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DNA End Resection: Facts and Mechanisms

DNA double-strand breaks (DSBs), which arise following exposure to a number of endogenous and exogenous agents, can be repaired by either the homologous recombination (HR) or non-homologous end-joining (NHEJ) pathways in eukaryotic cells. A vital step in HR repair is DNA end resection, which generat...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936662/
https://www.ncbi.nlm.nih.gov/pubmed/27240470
http://dx.doi.org/10.1016/j.gpb.2016.05.002