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Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization

Drug discovery efforts have focused on the tumor microenvironment in recent years. However, few studies have characterized the stroma component in patient-derived xenografts (PDXs) and genetically engineered mouse models (GEMs). In this study, we characterized the stroma in various models of breast...

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Detalles Bibliográficos
Autores principales: Vallerand, David, Massonnet, Gérald, Kébir, Fatima, Gentien, David, Maciorowski, Zofia, De la Grange, Pierre, Sigal-Zafrani, Brigitte, Richardson, Marion, Humbert, Sandrine, Thuleau, Aurélie, Assayag, Franck, de Plater, Ludmilla, Nicolas, André, Scholl, Suzy, Marangoni, Elisabetta, Weigand, Stefan, Roman-Roman, Sergio, Savina, Ariel, Decaudin, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936680/
https://www.ncbi.nlm.nih.gov/pubmed/27388901
http://dx.doi.org/10.1371/journal.pone.0157670