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PrP(C) Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells
The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI). While the misfolded PrP(Sc) scrapie isoform is the infectious agent of prion disease, the cellular isoform (PrP(...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936696/ https://www.ncbi.nlm.nih.gov/pubmed/27389581 http://dx.doi.org/10.1371/journal.pone.0157991 |