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PrP(C) Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells

The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI). While the misfolded PrP(Sc) scrapie isoform is the infectious agent of prion disease, the cellular isoform (PrP(...

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Detalles Bibliográficos
Autores principales:	Arkhipenko, Alexander, Syan, Sylvie, Victoria, Guiliana Soraya, Lebreton, Stéphanie, Zurzolo, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936696/ https://www.ncbi.nlm.nih.gov/pubmed/27389581 http://dx.doi.org/10.1371/journal.pone.0157991

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