The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis

Mitochondria must buffer the risk of proteotoxic stress to preserve bioenergetics, but the role of these mechanisms in disease is poorly understood. Using a proteomics screen, we now show that the mitochondrial unfoldase-peptidase complex ClpXP associates with the oncoprotein survivin and the respir...

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Detalles Bibliográficos
Autores principales: Seo, Jae Ho, Rivadeneira, Dayana B., Caino, M. Cecilia, Chae, Young Chan, Speicher, David W., Tang, Hsin-Yao, Vaira, Valentina, Bosari, Silvano, Palleschi, Alessandro, Rampini, Paolo, Kossenkov, Andrew V., Languino, Lucia R., Altieri, Dario C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936714/
https://www.ncbi.nlm.nih.gov/pubmed/27389535
http://dx.doi.org/10.1371/journal.pbio.1002507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936714/
https://www.ncbi.nlm.nih.gov/pubmed/27389535
http://dx.doi.org/10.1371/journal.pbio.1002507

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