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Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?

The renal podocyte plays an important role in maintaining the structural integrity of the glomerular basement membrane. We have previously reported that patients with idiopathic nephrotic syndrome (INS) have increased IL-2 production. We hypothesized that podocytes express an IL-2 receptor (IL-2R) a...

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Detalles Bibliográficos
Autores principales: Zea, Arnold H., Stewart, Tyrus, Ascani, Jeannine, Tate, David J., Finkel-Jimenez, Beatriz, Wilk, Anna, Reiss, Krzysztof, Smoyer, William E., Aviles, Diego H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936730/
https://www.ncbi.nlm.nih.gov/pubmed/27389192
http://dx.doi.org/10.1371/journal.pone.0157907