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Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?
The renal podocyte plays an important role in maintaining the structural integrity of the glomerular basement membrane. We have previously reported that patients with idiopathic nephrotic syndrome (INS) have increased IL-2 production. We hypothesized that podocytes express an IL-2 receptor (IL-2R) a...
Autores principales: | Zea, Arnold H., Stewart, Tyrus, Ascani, Jeannine, Tate, David J., Finkel-Jimenez, Beatriz, Wilk, Anna, Reiss, Krzysztof, Smoyer, William E., Aviles, Diego H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936730/ https://www.ncbi.nlm.nih.gov/pubmed/27389192 http://dx.doi.org/10.1371/journal.pone.0157907 |
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