A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus

In human cytomegalovirus (HCMV), tropism to epithelial and endothelial cells is dependent upon a pentameric complex (PC). Given the structure of the placenta, the PC is potentially an important neutralizing antibody target antigen against congenital infection. The guinea pig is the only small animal...

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Detalles Bibliográficos
Autores principales: Coleman, Stewart, Choi, K. Yeon, Root, Matthew, McGregor, Alistair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936736/
https://www.ncbi.nlm.nih.gov/pubmed/27387220
http://dx.doi.org/10.1371/journal.ppat.1005755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936736/
https://www.ncbi.nlm.nih.gov/pubmed/27387220
http://dx.doi.org/10.1371/journal.ppat.1005755

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