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The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

BACKGROUND: In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine against Onchocerca volvulus would provide a critical...

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Detalles Bibliográficos
Autores principales: Hess, Jessica A., Zhan, Bin, Torigian, April R., Patton, John B., Petrovsky, Nikolai, Zhan, Tingting, Bottazzi, Maria Elena, Hotez, Peter J., Klei, Thomas R., Lustigman, Sara, Abraham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936747/
https://www.ncbi.nlm.nih.gov/pubmed/27387453
http://dx.doi.org/10.1371/journal.pntd.0004797