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The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice
BACKGROUND: In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine against Onchocerca volvulus would provide a critical...
Autores principales: | Hess, Jessica A., Zhan, Bin, Torigian, April R., Patton, John B., Petrovsky, Nikolai, Zhan, Tingting, Bottazzi, Maria Elena, Hotez, Peter J., Klei, Thomas R., Lustigman, Sara, Abraham, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936747/ https://www.ncbi.nlm.nih.gov/pubmed/27387453 http://dx.doi.org/10.1371/journal.pntd.0004797 |
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