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Prophylactic administration of an extract from Plantaginis Semen and its major component aucubin inhibits mechanical allodynia caused by paclitaxel in mice

The chemotherapeutic agent paclitaxel (PTX) causes peripheral neuropathy as a major dose-limiting side effect, and this peripheral neuropathy is difficult to control. Our previous report showed that prophylactic repetitive administration of goshajinkigan (牛車腎氣丸 niú chē shèn qì wán), but not hachimij...

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Detalles Bibliográficos
Autores principales: Andoh, Tsugunobu, Kato, Mitsuru, Kitamura, Ryo, Mizoguchi, Shizuka, Uta, Daisuke, Toume, Kazufumi, Komatsu, Katsuko, Kuraishi, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936767/
https://www.ncbi.nlm.nih.gov/pubmed/27419098
http://dx.doi.org/10.1016/j.jtcme.2015.12.001