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Prophylactic administration of an extract from Plantaginis Semen and its major component aucubin inhibits mechanical allodynia caused by paclitaxel in mice
The chemotherapeutic agent paclitaxel (PTX) causes peripheral neuropathy as a major dose-limiting side effect, and this peripheral neuropathy is difficult to control. Our previous report showed that prophylactic repetitive administration of goshajinkigan (牛車腎氣丸 niú chē shèn qì wán), but not hachimij...
Autores principales: | Andoh, Tsugunobu, Kato, Mitsuru, Kitamura, Ryo, Mizoguchi, Shizuka, Uta, Daisuke, Toume, Kazufumi, Komatsu, Katsuko, Kuraishi, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936767/ https://www.ncbi.nlm.nih.gov/pubmed/27419098 http://dx.doi.org/10.1016/j.jtcme.2015.12.001 |
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