Cargando…

Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake

BACKGROUND: Though overexpression of epidermal growth factor receptor (EGFR) in several forms of cancer is considered to be an important prognostic biomarker related to poor prognosis, clear correlations between biomarker assays and patient management have been difficult to establish. Here, we utili...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Qing, Wållberg, Helena, Grafström, Jonas, Lu, Li, Thorell, Jan-Olov, Hägg Olofsson, Maria, Linder, Stig, Johansson, Katarina, Tegnebratt, Tetyana, Arnér, Elias S. J., Stone-Elander, Sharon, Ahlzén, Hanna-Stina Martinsson, Ståhl, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936982/
https://www.ncbi.nlm.nih.gov/pubmed/27388754
http://dx.doi.org/10.1186/s13550-016-0213-8