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Transcriptional reprogramming of metabolic pathways in critically ill patients

BACKGROUND: Critical illness causes a shift away from mitochondrial metabolism towards a greater dependence on glycolysis. This metabolic shift is thought to be associated with lactic acidosis, organ dysfunction and poor clinical outcomes. The current paradigm is that low oxygen supply causes region...

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Detalles Bibliográficos
Autores principales: Nalos, Marek, Parnell, Grant, Robergs, Robert, Booth, David, McLean, Anthony S., Tang, Benjamin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936987/
https://www.ncbi.nlm.nih.gov/pubmed/27387528
http://dx.doi.org/10.1186/s40635-016-0094-1