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Transcriptional reprogramming of metabolic pathways in critically ill patients
BACKGROUND: Critical illness causes a shift away from mitochondrial metabolism towards a greater dependence on glycolysis. This metabolic shift is thought to be associated with lactic acidosis, organ dysfunction and poor clinical outcomes. The current paradigm is that low oxygen supply causes region...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936987/ https://www.ncbi.nlm.nih.gov/pubmed/27387528 http://dx.doi.org/10.1186/s40635-016-0094-1 |