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Sickle Cells Abolish Melanoma Tumorigenesis in Hemoglobin SS Knockin Mice and Augment the Tumoricidal Effect of Oncolytic Virus In Vivo

Insights from the study of cancer resistance in animals have led to the discovery of novel anticancer pathways and opened new venues for cancer prevention and treatment. Sickle cells (SSRBCs) from subjects with homozygous sickle cell anemia (SCA) have been shown to target hypoxic tumor niches, induc...

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Detalles Bibliográficos
Autores principales: Sun, Chiang Wang, Willmon, Candice, Wu, Li-Chen, Knopick, Peter, Thoerner, Jutta, Vile, Richard, Townes, Tim M., Terman, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937018/
https://www.ncbi.nlm.nih.gov/pubmed/27458571
http://dx.doi.org/10.3389/fonc.2016.00166