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Mycobacterium leprae Activates Toll-Like Receptor-4 Signaling and Expression on Macrophages Depending on Previous Bacillus Calmette-Guerin Vaccination

Toll-like receptor (TLR)-1 and TLR2 have been shown to be receptors for Mycobacterium leprae (M. leprae), yet it is unclear whether M. leprae can signal through alternative TLRs. Other mycobacterial species possess ligands for TLR4 and genetic association studies in human populations suggest that pe...

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Detalles Bibliográficos
Autores principales: Polycarpou, Anastasia, Holland, Martin J., Karageorgiou, Ioannis, Eddaoudi, Ayad, Walker, Stephen L., Willcocks, Sam, Lockwood, Diana N. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937034/
https://www.ncbi.nlm.nih.gov/pubmed/27458573
http://dx.doi.org/10.3389/fcimb.2016.00072