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Development of Cerebral Microbleeds in the APP23-Transgenic Mouse Model of Cerebral Amyloid Angiopathy—A 9.4 Tesla MRI Study

Background: Cerebral amyloid angiopathy (CAA) is characterized by extracellular deposition of amyloid β (Aβ) around cerebral arteries and capillaries and leads to an increased risk for vascular dementia, spontaneous lobar hemorrhage, convexal subarachnoid hemorrhage, and transient focal neurological...

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Detalles Bibliográficos
Autores principales: Reuter, Björn, Venus, Alexander, Heiler, Patrick, Schad, Lothar, Ebert, Anne, Hennerici, Michael G., Grudzenski, Saskia, Fatar, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937037/
https://www.ncbi.nlm.nih.gov/pubmed/27458375
http://dx.doi.org/10.3389/fnagi.2016.00170