MicroRNA degeneracy and pluripotentiality within a Lavallière-tie architecture confers robustness to gene expression networks

Modularity, feedback control, functional redundancy and bowtie architecture have been proposed as key factors that confer robustness to complex biological systems. MicroRNAs (miRNAs) are highly conserved but functionally dispensable. These antinomic properties suggest that miRNAs fine-tune gene expr...

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Detalles Bibliográficos
Autores principales: Bhajun, Ricky, Guyon, Laurent, Gidrol, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Visions and Reflections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937071/
https://www.ncbi.nlm.nih.gov/pubmed/27038488
http://dx.doi.org/10.1007/s00018-016-2186-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937071/
https://www.ncbi.nlm.nih.gov/pubmed/27038488
http://dx.doi.org/10.1007/s00018-016-2186-1

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